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Generic Name : Atorvastatin
Brand name : Lipitor
Manufacturer: Pfizer
Why is Lipitor prescribed?
Lipitor is a cholesterol-lowering drug. Your doctor may prescribe it along with
a special diet if your blood cholesterol or triglyceride level is high enough to
put you in danger of heart disease, and you have been unable to lower your
readings by diet alone.
Atorvastatin calcium works by helping to clear harmful low density lipoprotein (LDL)
cholesterol out of the blood and by limiting the body's ability to form new LDL
cholesterol.
Most important fact about Lipitor
Lipitor is usually prescribed only if diet, exercise, and weight loss fail to
bring your cholesterol levels under control. It's important to remember that
Lipitor is a supplement--not a substitute--for those other measures. To get the
full benefit of the medication, you need to stick to the diet and exercise
program prescribed by your doctor. All these efforts to keep your cholesterol
levels normal are important because they may lower your risk of heart disease.
How should you take Lipitor?
Lipitor should be taken once a day, with or without food. You can take it in the
morning or the evening, but should hold to the same time each day. The drug
generally begins working within 2 weeks.
For an even greater cholesterol-lowering effect, your doctor may prescribe
Lipitor along with a different kind of lipid-lowering drug such as Questran or
Colestid. It's important to avoid taking the two drugs at the same time of day.
Take Lipitor at least 1 hour before or 4 hours after the other drug.
-- If you miss a dose…
Take the forgotten dose as soon as you remember. If it is almost time for your
next dose, skip the one you missed and go back to your regular schedule. Do not
take 2 doses at the same time.
-- Storage instructions…
Store at room temperature.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity,
inform your doctor as soon as possible. Only your doctor can determine if it is
safe for you to continue taking Atorvastatin calcium. The side effects of
Lipitor--if any develop--are usually mild.
Side effects may include:
Abdominal pain, abnormal heartbeat, accidental injury, acne, allergic reaction,
amnesia, back pain, black stools, bleeding, breast enlargement, changes in
eyesight, changes in taste sensation, chest pain, constipation, decreased sex
drive, depression, diarrhea, difficulty swallowing, distorted facial muscles,
dizziness, dry eyes, fatigue, fever, flu symptoms, fluid retention, gas, hair
loss, headache, hearing difficulties, heartburn, increased muscle movement,
increased sensations, indigestion, inflammation of sinus and nasal passages,
insomnia, itching, joint pain, lack of coordination, leg cramps, muscle aching
or weakness, purple or red spots on the skin, rash, respiratory problems,
ringing in the ears, sensitivity to light, skin irritations, sore throat,
strange dreams, sweating, tingling of extremities, unstable emotions, urinary
problems, vomiting, weakness, weight gain, weight loss
Why should Lipitor not be prescribed?
Never take Lipitor during pregnancy or while breastfeeding. You should also
avoid Atorvastatin calcium if you have liver disease, or if the drug gives you
an allergic reaction.
Special warnings about Lipitor.
There is a slight chance of liver damage from Lipitor, so your doctor may order
a blood test to check your liver function before you start taking the drug,
again 12 weeks after you begin therapy or your dosage is increased, and every 6
months thereafter. If the tests reveal a problem, you may have to stop using
Atorvastatin calcium.
Drugs like Lipitor have occasionally been known to damage muscle tissue, so be
sure to tell your doctor immediately if you notice any unexplained muscle
tenderness, weakness, or pain, especially if you also have a fever or feel sick.
Your doctor may want to do a blood test to check for signs of muscle damage.
Possible food and drug interactions.
If you take Lipitor with certain other drugs, the effects of either could be
increased, decreased, or altered. It is especially important to check with your
doctor before combining Lipitor with any of the following:
- Antacids such as Maalox TC Suspension
- Colestipol (Colestid)
- Cyclosporine (Sandimmune, Neoral)
- Digoxin (Lanoxin)
- Erythromycin (E.E.S., Erythrocin, others)
- Fluconazole (Diflucan)
- Gemfibrozil (Lopid)
- Itraconazole (Sporanox)
- Ketoconazole (Nizoral)
- Niacin (Niaspan, Niacor, Slo-Niacin)
- Oral contraceptives
Special information.
Developing babies need plenty of cholesterol, so this cholesterol-lowering drug
should never be used during pregnancy. In fact, your doctor is unlikely to
prescribe Lipitor if there is even a chance that you may become pregnant. If you
do conceive while taking this drug, notify your doctor right away. Lipitor does
make its way into breast milk, so you should not take the drug while
breastfeeding your baby.
Recommended dosage.
You need to follow a standard cholesterol-lowering diet before starting Lipitor,
and should continue following it throughout your therapy.
ADULTS
The usual starting dose is 10 milligrams once a day, with or without food. The
doctor will check your cholesterol levels every 2 to 4 weeks and adjust the dose
accordingly. The maximum recommended daily dose is 80 milligrams.
CHILDREN
Use in children is rare. The drug has never been prescribed for children under 9
years of age.
Overdosage.
Although no specific information about Lipitor overdose is available, any
medication taken in excess can have serious consequences. If you suspect an
overdose of Lipitor, seek medical attention.
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